diff --git a/mitmproxy/builtins/replace.py b/mitmproxy/builtins/replace.py
index c938d6838..df3cab043 100644
--- a/mitmproxy/builtins/replace.py
+++ b/mitmproxy/builtins/replace.py
@@ -36,9 +36,9 @@ class Replace:
         for rex, s, cpatt in self.lst:
             if cpatt(f):
                 if f.response:
-                    f.response.replace(rex, s)
+                    f.response.replace(rex, s, flags=re.DOTALL)
                 else:
-                    f.request.replace(rex, s)
+                    f.request.replace(rex, s, flags=re.DOTALL)
 
     def request(self, flow):
         if not flow.reply.has_message:
diff --git a/mitmproxy/filt.py b/mitmproxy/filt.py
index 67915e5b6..eb3e392bf 100644
--- a/mitmproxy/filt.py
+++ b/mitmproxy/filt.py
@@ -244,6 +244,7 @@ class FHeadResponse(_Rex):
 class FBod(_Rex):
     code = "b"
     help = "Body"
+    flags = re.DOTALL
 
     @only(HTTPFlow, TCPFlow)
     def __call__(self, f):
@@ -264,6 +265,7 @@ class FBod(_Rex):
 class FBodRequest(_Rex):
     code = "bq"
     help = "Request body"
+    flags = re.DOTALL
 
     @only(HTTPFlow, TCPFlow)
     def __call__(self, f):
@@ -280,6 +282,7 @@ class FBodRequest(_Rex):
 class FBodResponse(_Rex):
     code = "bs"
     help = "Response body"
+    flags = re.DOTALL
 
     @only(HTTPFlow, TCPFlow)
     def __call__(self, f):