diff --git a/setup.py b/setup.py
index 467a29ba2..fd7918f14 100644
--- a/setup.py
+++ b/setup.py
@@ -71,7 +71,7 @@ setup(
         "Brotli>=1.0,<1.1",
         "certifi>=2019.9.11",  # no semver here - this should always be on the last release!
         "click>=7.0,<8",
-        "cryptography>=3.3,<3.4",
+        "cryptography>=3.3,<3.5",
         "flask>=1.1.1,<1.2",
         "h11>=0.11,<0.13",
         "h2>=4.0,<5",
@@ -80,11 +80,11 @@ setup(
         "ldap3>=2.8,<2.10",
         "msgpack>=1.0.0, <1.1.0",
         "passlib>=1.6.5, <1.8",
-        "protobuf>=3.14,<3.15",
+        "protobuf>=3.14,<3.16",
         "pyOpenSSL>=20.0,<20.1",
         "pyparsing>=2.4.2,<2.5",
         "pyperclip>=1.6.0,<1.9",
-        "ruamel.yaml>=0.16,<0.17",
+        "ruamel.yaml>=0.16,<0.18",
         "sortedcontainers>=2.3,<2.4",
         "tornado>=4.3,<7",
         "urwid>=2.1.1,<2.2",
@@ -97,7 +97,7 @@ setup(
             "pydivert>=2.0.3,<2.2",
         ],
         'dev': [
-            "hypothesis>=5.8,<6.2",
+            "hypothesis>=5.8,<6.9",
             "parver>=0.1,<2.0",
             "pdoc>=4.0.0",
             "pytest-asyncio>=0.10.0,<0.14,!=0.14",
diff --git a/tox.ini b/tox.ini
index 1e71f2ae2..1a08d2ebb 100644
--- a/tox.ini
+++ b/tox.ini
@@ -28,7 +28,7 @@ commands =
   python ./test/filename_matching.py
 
 [testenv:mypy]
-deps = mypy==0.800
+deps = mypy==0.812
 commands =
   mypy {posargs}
   
@@ -41,7 +41,7 @@ passenv = CI_* GITHUB_* AWS_* TWINE_* DOCKER_*
 deps =
   -e .[dev]
   pyinstaller==4.2
-  twine==3.3.0
+  twine==3.4.1
   awscli
 commands =
   mitmdump --version